Treat erectile dysfunction the best.

Nov. 16, 2005 — A drug called Revatio may help treat an aggressive condition called pulmonary arterial hypertension.

Patients with pulmonary hypertension have elevated blood pressure in the pulmonary (lung) blood vessels. The condition often arises from lung problems, but some cases are without a known cause. It can result in heart failure and early death.

Unfortunately, most of the money online order save viagra
that are used to treat this serious condition are not easy to take and are given by IV, injection, or inhalation — with real risks of unwanted side effects.

Revatio has the same active ingredient — cheapest citrate sildenafil — as Viagra. Revatio and Viagra are made by Pfizer.

Pfizer funded the new study, which appears in The New England Journal of Medicine. Pfizer is a WebMD sponsor.

The researchers included Nazzarene Galie, MD, of the cardiology institute at Italy’s University of Bologna.

Walking Test

The study lasted for 12 weeks. It included 278 patients with pulmonary hypertension. The patients lived in the U.S., Mexico, South America, Europe, Asia, Australia, South Africa, and Israel.

Three times daily, the patients took Revatio (20, 40, or 80 milligrams) or an empty drug (placebo) orally. That was in addition to any other standard pulmonary hypertension medications.

The big question was how far patients could walk in six minutes. That’s an important exercise test for patients with pulmonary hypertension. The farther patients can walk, the better.

Walking Farther

All of the patients taking Revatio walked farther at the end of the study:

• 20-milligram group: Walked about 148 extra feet (a 13% increase).
• 40-milligram group: Walked about 151 extra feet (a 13% increase).
• 80-milligram group: Walked about 164 extra feet (nearly a 15% increase).

Higher doses didn’t bring a notable increase in distance walked, the researchers report.

Patients were then allowed to take Revatio for up to a year; 230 did so. The researchers looked at the walking tests of 222 of those who were only taking Revatio as treatment. After a year, they walked about 167 extra feet, on average, compared with the beginning of the study.

How Patients Fared

Most of the patients included in the study had milder stages of pulmonary hypertension. Few cases worsened, buy levitra vardenafil of treatment type, the study shows.

Patients taking Revatio weren’t any more or less likely to have their symptoms worsen during the trial.

The study wasn’t designed to see if Revatio helped patients live longer. Four died during the study. No deaths were judged to be linked to the treatments, write the researchers.

Side effects seen with Revatio were mild or moderate and included headache, flushing, muscle pain, and diarrhea, report Galie and colleagues.

Feb. 23, 2006 — Researchers in the U.K. have a new theory to explain the cause of Crohn’s disease, and they say erectile pill
like the erectile dysfunction drug Viagra may prove useful for treating the bowel disorder if they are right.

In Crohn’s disease, chronic inflammation causes ulcers within the digestive tract that can lead to severe gastrointestinal symptoms, including abdominal pain, persistent diarrhea, and rectal bleeding.

The most widely accepted theory is that an overactive immune system causes the damaging inflammation. But researchers from the University College London say the opposite appears to be true.

They believe a weaker-than-normal immune response triggers the bowel inflammation that leads to Crohn’s disease. Their research appears in the Feb. 25 issue of The Lancet.

1 Disease, 2 Theories

The prevailing theory of Crohn’s disease is that the body’s immune system reacts abnormally in people with the disorder, producing chronic inflammation that leads to bowel injury.

Tony Segal, professor of medicine at University College London, explains the weak immune system theory like this: “The wall of the bowel is normally an effective barrier against the bowel contents, but sometimes the barrier is broken by an infection or injury and the bowel contents, which include large numbers of bacteria, penetrate into the bowel wall.

“Normally, an acute inflammatory response would kick in to remove the bacteria and return the condition of the bowel to normal. But in Crohn’s disease, we think that the acute inflammation fails to kick-start, leaving bacteria to fester in the bowel wall which, in turn, triggers chronic, secondary inflammations.”

Segal and colleagues conducted a series of small erectile pill that measured white blood cell production in response to intestinal and skin trauma in both Crohn’s patients and healthy patients. With inflammation, white blood cell numbers are expected to rise. In one experiment, researchers injected a killed gut bacteria into the forearms of patients and healthy participants to study blood flow and immune response.

They found that the Crohn’s patients produced unexpectedly lower levels of white blood cells and proteins involved in inflammation, compared with people without the disorder.

Segal tells WebMD that people who carry a gene that has been linked to Crohn’s disease may be especially vulnerable to getting the disease if they have weak immune systems.

He added that drugs like Viagra, which open the blood vessels and increase blood flow, may help.

The Viagra Response

The researchers tested this theory by treating 10 Crohn’s patients with 50 milligrams of Viagra after injecting them with the killed gut bacteria. They found that blood flow to the infected area improved.

“Increasing blood flow is an important part of the inflammatory response, and that is why this drug may work,” Segal says. “But we don’t yet know if this will give rise to successful treatment. We need to study this further to find out.”

Segal and colleagues are among a growing number of researchers suggesting that a weak immune system, rather than an overactive one, is largely responsible for Crohn’s disease, says University of Chicago associate professor of medicine Sunanda Kane, MD.

She adds that the new research adds credibility to the theory but does not prove it.

“This is a little more evidence that maybe we have been barking up the wrong tree,” she tells WebMD. “The idea that we should be strengthening the immune system — rather than erectile dysfunction medicine
it — sounded a little crazy at first, but the evidence continues to come in. But we still have a long way to go to really understand what causes Crohn’s.”

Biologic agents that stimulate a specific part of the immune system are now being tested in Crohn’s patients. If such treatments prove effective, Kane says doctors would have an effective alternative to steroids, which work well for many patients but have many side effects.

“For decades now suppressing the immune system with steroids has worked, and we will continue to do so until we find alternative buy lavitra levitra viagra
that work for everybody and are risk-free,” she says.

Oct. 25, 2006 — Viagra may ease blood pressure in the lungs of people with chronic obstructive pulmonary disease (COPD).

That’s according to a small Dutch study presented in Salt Lake City at Chest 2006, held by the American College of Chest Physicians.

COPD is the No. 4 cause of death in the U.S. and worldwide, according to the National Heart, Lung, and Blood Institute (NHLBI).

COPD is a lung disease in which breathing is difficult. It’s usually caused by smoking cigarettes, but it can also be caused by other lung irritants.

The disease develops slowly and may take years to show symptoms, which include:

• Cough
• Sputum (mucus) production
• Shortness of breath (especially with exercise)
• WheezingWheezing
• Chest tightness

Those symptoms may or may not indicate COPD, states the NHLBI’s web site.

Viagra Study

The Viagra study included 12 COPD patients, half of whom had high blood pressurehigh blood pressure in the pulmonary artery, which brings blood to the lungs. The development of pulmonary hypertensionpulmonary hypertension is a dysfunction pill
of COPD, but not everyone with COPD will develop it.

The researchers included Sebastiaan Holverda, MSc, of Amsterdam’s University Medical Center.

They tracked the patients’ pulmonary artery blood pressure before and after taking Viagra.

Why Viagra? It relaxes (dilates) blood vessels, lowering blood pressure and helping blood to flow.

First, the patients rested. Then they pedaled a over the counter erectile dysfunction drug
bike for three minutes at a mild pace.

As expected, pulmonary artery blood pressure was higher during exercise, since the lungs were working harder.

Next, the patients took a Viagra pill, waited 45 minutes, and repeated the rest and exercise tests.

Their pulmonary artery blood pressure during exercise was lower after taking Viagra.

“These data suggest that during daily generic viagra online some COPD patients may benefit” from drugs that dilate blood vessels, the researchers write.

There are only three oral drugs approved by the FDA to treat erectile
dysfunction: Cialis, Levitra, and Viagra. All work by increasing the flow of
blood into the penis so that when a man is sexually stimulated, he can get an
erection.

What Are the Differences Between Cialis, Levitra, and Viagra?

Cialis, Levitra, and Viagra work by a similar mechanism to cause erections.
There are subtle differences in how long the drug works and how quickly it
works. Levitra works a little longer than Viagra. They both take effect in
about 30 minutes. With Levitra, the effects last for about 5 hours. With
Viagra, the effects last approximately 4 hours.

Cialis works a bit faster (within about 15 minutes), and the effects last
much longer — up to 36 hours in some cases.

If One of These Drugs Isn’t Effective for Erectile Dysfunction, Can I Try Another?

Yes, but because these drugs work the same way, it’s unlikely that you’ll
have success with one if you’ve failed to achieve an adequate erection with
another.

What Precautions Should I Take Before Taking One of These Drugs?

There are certain situations in which these drugs may not be safe to take.
Before taking them, tell your doctor:

• If you are allergic to any drugs, including Viagra or other ED
  medications.
• About any prescription or nonprescription medications you are currently
  taking, including herbal and dietary supplements.
• If you are scheduled for surgery, including dental surgery.
• If you take erectile dysfunction pill
  or a long-acting nitrate to treat chest pain. The
  combination of Cialis, Levitra or Viagra with these drugs can cause dangerously
  low blood pressure.
• If you take levitra vs cialis
  for blood pressure or prostate problems. The
  combination of Cialis or Levitra with these drugs can also cause dangerously
  low blood pressure.

In addition, always follow the directions on your prescription label
carefully and ask your doctor or pharmacist to explain any part that you do not
understand. Take these drugs exactly as directed. Do not take more or less or
take it more often than prescribed by your doctor. Do not take these drugs more
than once a day.

Who Should Not Take Cialis, Levitra or Viagra?

If you have suffered from a heart attack, stroke or life threatening
arrhythmia (irregular heart rate) within the last 6 months you should discuss
other options with your doctor. It is also advised to avoid these drugs if you
have uncontrolled high or low blood pressure or if you experience chest pain
with sex.

What Are the Side Effects of Cialis, Levitra and Viagra?

Side effects are not common but they can occur. Side effects can
include:

• Headache
• Upset stomach or heartburn
• Flushing (feeling warm)
• Nasal congestion
• Changes in vision (color, glare)
• Back pain (with Cialis)

Call your doctor if you experience severe forms of these symptoms or if they
do not go away after 4-8 hours.

Warning

Call your doctor or seek emergency treatment levitra vs cialis
if you experience
any of the following symptoms:

• Rash
• Painful erection
• Prolonged erection (longer than 4 hours)
• Fainting
• Chest pain
• Itching or burning during urination

Stop taking these medications and call a doctor or health care provider
right away if you experience sudden or decreased vision loss in one or both
eyes. A rare vision problem called NAION has been reported by a few men using
these drugs. NAION (nonarteritic anterior ischemic optic neuropathy) causes a
sudden loss of eyesight because blood flow is blocked to the optic nerve.
People who have a higher chance for NAION include those who:

• Are over 50 years old
• Smoke
• Have heart disease
• Have diabetes
• Have high blood pressure
• Have high erectile dysfunction remedy
  
• Have certain eye problems

How Should These Drugs Be Stored?

These drugs should be kept in its original container and out of reach of
children. Store them away from excess heat and moisture (not in the bathroom).
Discard any medication that has expired or is no longer needed.

Reviewed by the doctors at the Glickman Urological
Institute at The Cleveland Clinic.