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NEW YORK - To help the pharmaceutical industry combat drug erection problem, IBM is launching an electronic pedigree system Thursday that tracks medications through the supply chain until they reach consumers.

The system employs radio-frequency identification, or RFID tags, which are already used to track packages of drugs, especially ones popular with counterfeiters. Pfizer, for example, uses RFID chips to track packs of its erectile dysfunction drug Viagra, and Purdue Pharma LP has been using them since 2004 to track its pain reliever OxyContin.

IBM’s ePedigree system helps drug companies create electronic certificates of authenticity for medications &151; as they move from brand drug generic name viagra and distributors to pharmacies and hospitals.

“The whole time, the system is watching what’s happening, it records (the drug’s) life history,” said Chris Clauss, director of sensor information management at IBM Software.

While there is no guarantee that RFID tags will get rid of all counterfeits, he added, “what we can do is raise the bar,” and make it substantially more difficult.

Drug companies’ prior attempts at fighting fakes &151; were often reproduced within months, to the point where even their brand managers could not tell the difference between the counterfeit and the real thing.

IBM, which first worked with RFID more than 10 years ago, said its ePedigree system will help companies comply with a slew of new regulations, such as ones going into effect in California in 2009.

California’s ePedigree law will require that any medication distributed in the state have its life history attached to it &151; how the data is scanned and collected in the chips — said Michael Liard, research director of RFID and Contactless at ABI Research. IBM’s ePedigree system, however, focuses on how that information is distributed along the supply chain.

The ePedigree system is useful not just for battling fakes, Clauss said, but for keeping track of expiration dates, batch numbers in case a drug is recalled, and so on.

Sale viagra Business Machines Corp. is based in Armonk, N.Y.

Source IBM launches system to track medications article

Read more on News - How to make spam unstoppable site
Good news for spammers, the smart filtering software used to catch spam can be beaten.

With a little ingenuity it is possible to create messages that get past anti-spam filters every single time.

The discovery has been made by anti-spam generic lines viagra John Graham-Cumming who studies the novel ways spammers try to defeat the technologies used to stop junk mail.

The bad news for spammers is that this flaw in filtering systems is not easy to exploit and can be combated.

Ham versus spam

If you have an e-mail address you will know about spam and the longer you have had that address the more spam you will get. It is estimated that 60% of all messages sent are now spam.

To cut out the junk, many e-mail users have turned to a technology known as Bayesian filtering to spot and stop spam before it reaches their in-box.

When trained to spot what is spam and what is legitimate mail these smart filters can catch, in many cases, more than 99% of junk messages.

INTERNET MAIL SPAM FIGURES 60% - January 2004 58% - December 2003 56% - November 2003 52% - October 2003 54% - September 2003 50% - August 2003 50% - July 2003 49% - June 2003 48% - May 2003 46% - April 2003 45% - March 2003 42% - February 2003 Source: Brightmail

The smart filtering has been so successful that it has already forced a change in the way spam messages are written.

Random words are being added to some messages specifically to fool the filters.

“They are looking for things that are not spammy,” said Mr Graham-Cumming, “words that outweigh the encyclopedia health treatment yahoo of the message.”

This is the reason that many spam messages feature rarely used words such as “formic”, “brouhaha”, “granitic” and “occlusive”.

Cheap generic viagra, it does not work.

“It’s a completely ineffective technique,” he said.

Filter flaw

But Mr Graham-Cumming, who is a member of the Sophos Anti-Spam Task Force, has found a way to beat Bayesian filters that guarantees a message will get through every time.

Viagra is hawked by many spammers

He was prompted to investigate the weaknesses of Bayesian filters because, although he uses them himself, some messages still get through.

To find out how to beat the filters Mr Graham-Cumming sent himself the same message 10,000 times but to each one added a fixed number of random words.

When a message got through he trained an “evil” filter that helped to tune the perfect collection of additional words.

Soon he had generated a short list of words that, if added to a spam message, would guarantee its safe passage into his inbox.

“The actual words it found were a total surprise,” said Mr Graham-Cumming.

The list included words such as “Berkshire”, “Marriott”, “wireless”, “touch” and “comment”.

Including just one of these words convinced Mr Graham-Cumming’s real spam filter that a message was ham rather than spam.

My Graham-Cumming said defending against spam that uses these words would be very difficult because the words are tied to a person’s job and lifestyle.

But, he said, the good news is that the technique to discover these trigger words is very time consuming.

He had to send himself thousands of copies of the same message each one holding an encoded chunk of HTML that reported back to him when it got past the filter.

These HTML bugs can be thwarted by turning off the preview pane in e-mail.

And, he said, this would have to be repeated for every person a spammer wanted to reach because they would all have a different list of key words.

But, he said, although sending thousands of messages to one person would be counter-productive, sending fewer to a larger pool of people, such as all the staff at a business, might produce some key words for that business and help a spammer get their junk mail through.

Source MAN SHOULD REVEAL HIS MEDICAL CONDITION BEFORE GETTING MARRIED article

DEAR ABBY: I am a 40-year-old male who has been divorced for the last five years. I am considering trying marriage again, but am somewhat concerned about the impotence problem I have had for some time.

I have consulted many doctors and have taken many tests, but they all came out OK — so I decided to try Viagra. It has been working great.

Should I be upfront about my medical condition if and when I propose marriage, or should I wait until after we’re married? It is extremely embarrassing to talk about this to anyone, let alone a woman who might become my wife. — UNCERTAIN IN Viagra soft, CALIF.

DEAR UNCERTAIN: You should absolutely disclose any medical condition that could affect your marriage before you are married. Not to do so could be considered fraud. If the woman loves you, she will accept you just as you are.

However, when the time comes, it might be beneficial for you and your prospective fiancee to pay a visit to your physician together. It’s possible that your impotence may have been linked to the fact that your marriage didn’t work, and has nothing to do with your ability to perform without the little blue pills.

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DEAR ABBY: I recently lost my fiance to leukemia. He was only 27. I have noticed that the first words of comfort offered to me by people are, “You’re young and pretty. You’ll find someone again.” Abby, my fiance has been gone only four months. Several people said that to me at his funeral and wake!

I understand the thought behind those words — that my life will not end because his did. But it was extremely infree viagra sample before buying to hear something like that so soon after his death. I know I will eventually feel like dating again, but right now his loss is still too recent and painful.

How should I respond to people who say that? Please help me get the word out that this is no comfort so soon after someone’s partner passes away. — STILL MOURNING IN SAN FRANCISCO

DEAR STILL MOURNING: Please accept my deepest sympathy for your loss. Your sentiments have been repeated by others who have also suffered a loss.

For some reason, when there is a death, people feel they must say something to “fix” it — as if anything that could be said would make the pain go away.

Folks: The appropriate way to extend condolences is the simplest. Just repeat the first sentence of my answer. Period! That’s all! And do not ask questions about the cause of death. And when someone offers you condolences — a simple thank you is enough. Then, unless you wish to talk about it, change the subject.

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DEAR ABBY: My husband and I were invited to a friend’s home for dinner. We brought a lovely plant as a thank-you gift. When we arrived at her house, she said she had forgotten she had invited us for that night. We talked in her driveway for a few minutes, and I handed her the plant as we left. My question is, what was the correct thing to do? Should we have let her have the plant or taken it back home with us? — PERPLEXED IN MCCLEARY, WASH.

DEAR PERPLEXED: You didn’t mention how old this friend is, but she appears to be disorganized, overscheduled or suffering from mind-cognitive impairment. Although there are no rules of etiquette that dictated it, you were nice to leave the plant with her. Perhaps it will serve as a reminder to reschedule the dinner.

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Dear Abby is written by Abigail Van Buren, also known as Jeanne Phillips, and was founded by her mother, Pauline Phillips. Write Dear Abby at www.DearAbby.com or P.O. Box 69440, Los Angeles, CA 90069.

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To order “How to Write Letters for All Occasions,” send a business-sized, self-addressed envelope, plus check or money order for $6 (U.S. funds) to: Dear Abby — Letter Booklet, P.O. Box 447, Mount Morris, IL 61054-0447. (Postage is included in the price.)

The TV commercials make it all seem so simple: He can’t get an erection so he pops a pill. The next thing you know, his partner is cooing about how her guy is back to his old wild and romantic self. What the commercials don’t show you: The painful distress a woman can experience when her man suffers with erectile dysfunction (ED). “Women internalize things — they tend to blame themselves first, thinking it’s because they have done something wrong, or that they are no longer attractive to their partner. In fact, the first thing a woman thinks when a man can’t get an erection is that it’s her fault, and nothing could be further from the truth,” says Andrew McCullough, MD, director of sexual health and male buy viagra without a prescription at NYU Medical Center in New York City. ED, or erectile dysfunction, is medically defined as the inability to achieve or sustain an erection long enough for sexual intercourse. Virtually all men experience some erection failures at certain points in their lives. It can be the result of stress, depression, or sometimes even for no reason at all. For some, the problem becomes chronic. When it does, a diagnosis of ED is made. According to the American Foundation for Urologic Disease, it’s a problem that affects about 18 million men in the U.S. alone. Although many women — and men as well — continue to view ED as a sexual issue, in truth, the most common causes are undiagnosed physical conditions such as diabetes, high cholesterol, or even the earliest stages of heart disease. Even more often, it can be the result of certain medications used to treat these conditions, anxiety cialis soft treatment viagra some high blood pressure drugs. High blood pressure impotence, experts say a lack of education about the causes of ED are frequently behind a woman’s self-blame, as well as her increasing anxiety, and sometimes, even feelings of hurt and anger when the problem occurs. “Most women usually start with a line of erectile dysfunction help that often has some anxiety or hurt to it. She may suspect her partner is having an affair, or that he just doesn’t find her desirable anymore, so she begins to hint around at these possibilities,” says Sallie Foley, MSW, a professor at the graduate school of social work at the University of Michigan and co-author of Sex Matters For Women. Often, says Foley, a man suffering with ED will interpret her questions – and her hurtful attitude — as an attack on him, so he pulls back. “She then soft viagra tablet this pulling back as a confirmation that she has done something wrong, and so she retreats even further,” says Foley. As she does, increasing levels of anxiety or depression can set in, along with suspicions about what’s going on with him, as well as a continued belief that there is something wrong with her. The end result: The couple can stop communicating altogether — not only in the bedroom, but in all aspects of their relationship. And that, say experts, can only make problems worse for both partners. “The one thing a woman should never do is withdraw because that is a formula for relationship disaster,” says McCullough. When one partner pulls away, he says, the other withdraws as well, and “this kind of dance goes on where you stop touching each other, then you stop talking, and before you know it you are not communicating at all.” Read source on Women & Impotence: A Woman’s Point of View About Male Impotence

Top European pharmaceutical firms are using unscrupulous marketing practices to promote their products, a consumer report says.

The Consumers Cheapest citrate sildenafil lobby group accused drugmakers of using the methods to get doctors to prescribe products and persuade consumers they need them.

It said there was a “shocking” lack of publicity about where the $60bn (33bn) annual marketing spend went.

Drug firms say that they act within strict guidelines.

The Association of the British Pharmaceutical Industry (ABPI) told the BBC News website that for UK-based firms there was “a stringent and transparent code of practice that goes beyond the viagra soft tab of UK law and the industry regulator”.

Sponsorships

Consumers International said it had analysed the selling techniques of many leading companies, including Bayer, Soft viagra and Johnson & Johnson.

The current regulatory framework is clearly herbal cure for erectile dysfunction to prevent systemic violations of marketing regulations Consumers International

Richard Lloyd, the group’s director general, said: “The pharmaceutical industry spends nearly twice as much on marketing as it does on research and development, yet consumers know next to nothing about where this money is going.”

He called for a revision of marketing regulations to achieve “more transparency from drug companies”.

In most Western markets direct advertising to consumers is banned.

But Mr Lloyd said there were other methods drug companies were using to influence opinion.

These include the sponsoring of patient lobby groups, funding disease awareness campaigns and use of hospitality packages for medical experts.

As producers of life-saving medicines it is important that we ensure doctors know full details ABPI

The report cites sponsorships by such firms as Eli Lilly and Pfizer. The latter, the maker of Viagra, sponsored a campaign by the Impotence Association which sported the Pfizer logo.

The report said only one of the firms studied, Orion Pharma, provided specific marketing budget information.

It also pointed to the “large numbers of serious, recent and repeated breaches of marketing codes”.

This showed the “current regulatory framework is clearly insufficient to prevent systemic violations of marketing regulations”.

However, the ABPI said the number of complaints raised showed the system, which had been generic viagrageneric viagra this year, was working.

It said complaints from drug companies about fellow firms’ activities showed the self-regulation was effective.

But it also said it was vital for doctors to know about products.

“There is no point having innovative new medicines if they remain unused,” an association spokesman said.

Read more on News - Drug firms attacked on marketing site

Original article Viagra A Boon To Brothels (AP) Business has been real good for Joe Richards since spring and he credits Viagra. He’s no erectile dysfunction drug either, he owns two brothels. Richards figures the wildly popular impotence pill has increased activity at the Cherry Patch and Mabel’s by some 10 percent. “We have a lot of guys who used to come up here but stopped, and now they’re back. The girls say they’re on the pill,” said Richards. “We’re talking older fellows, in their 60s or older.” For all the talk about Viagra, its effectiveness boils down to what goes on behind closed doors. Until now, no one’s heard from those in the world’s oldest profession, and some are blindness causing citrate sildenafil happy with the new medicine. “I wish we could sell Viagra,” Richards said. “If we could advertise it and have it on the premises, we’d be in good shape.” Made by Pfizer Inc., Viagra is the first pill to treat male impotence. The company said there have been 1.7 million new prescriptions for the drug since March, 80 percent of them for men over 50. Doctors have warned patients not to combine Viagra with nitrates, some of which are found in heart medications. And deaths among men who took Viagra have climbed to 16, including seven who died during or after sex. The FDA said there is no evidence that Viagra is to blame for the deaths of the men, most of whom were in their 60s and 70s. Not that the deaths have scared off Viagra-packing visitors in Nevada, where prostitution is illegal in Reno and Las Vegas but allowed in some counties. There are some 30 brothels. Dennis Hof, owner of the Moonlight Bunnyranch and Miss Kitty’s Fantasy Ranch east of Carson City, said business at the brothels has increased by at least 20 percent since March. Bunnyranch manager Suzette Gwin said Viagra is the reason her customers say it’s so. “There have been some guys in here who look about 80,” Ms. Gwin said. “They come in with their canes. But the girls don’t care if their customers are 18 or 100 years old.” Not everyone buys the good news. George Flint, head of the Nevada Brothel Owner’s Condition dysfunction erectile more treatment, thinks the claim of a Viagra impact is all hype. “By the time you spend $10 for one pill, you can’t afford to go to the ranch,” said Flint, who also speaks for the fabled Mustang Ranch, east of Reno. “I discussed this with the manager at Mustang and she laughed and said there’s absolutely no impact,” Flint said. “Oh, sure, probably eight or 10 people have taken this impotence treatment erectile dysfunction treatment, but you have to realize there are half a million clients who come into Nevada brothels every year.” In fact, Flint said the effect of Viagra on Nevada’s brothel business probably amounts to less than 1 percent: “There’s no parade of old codgers coming in.”