Archive for March 10th, 2008
Heart Drug for Female Sexual Disorder?
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July 24, 2006 — Like Viagra before it, a drug once studied to treat heart problems may help treat sexual dysfunction. But this time it’s being tested article drug dysfunction erectile from internal medicine news rx update for women. A new study shows that a modified version of the experimental heart drug Candoxatril was effective at increasing blood flow to the vagina in animal tests. If further research confirms these results in humans, the drug may be used to treat female sexual arousal disorder (FSAD). Sildenafil citrate and discount say an estimated 40% of women suffer from FSAD or other forms of sexual dysfuction, such as low libido or pain during intercourse. Candoxatril went into clinical trials in the 1990s as a heart failureheart failure medication but has since become the focus of efforts to develop a medication to treat female sexual arousal disorder. How the Drug WorksCandoxatril is one of several compounds that targets levels of vasoactive intestinal peptide (VIP), which controls blood flow to the vagina. Researchers say decreased blood flow to the vagina is thought to be a key factor in female sexual arousal disorder. An enzyme called NEP degrades VIP in the body, and Candoxatril works by blocking NEP. In a new study, published in the Journal of Medicinal Chemistry, researchers altered the molecular structure of Candoxatril in order to focus the drug to treat female sexual arousal dysfunction. In animal tests, researchers at Pfizer Global Research and Erectile dysfunction drugs They say the results suggest that the drug might have similar effects in humans, but further research is needed. |
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